Don't Ignore Your Gut Issues

stephiehenson250
Sep 6
2 min read

How Many Diseases Begin in the Gut?

A very large proportion of chronic diseases have their origins, or at least strong contributing factors, in the gut.

Why the Gut is Central

Around 70–80% of the immune system is located in the gut.
The gut microbiome helps regulate immunity, metabolism, inflammation, and even brain and hormonal health.
The gut lining acts as a barrier. If compromised (“leaky gut”), unwanted substances can enter the bloodstream and trigger inflammation and disease.

Diseases Linked to Gut Health

Digestive diseases (direct origin): IBS, IBD, coeliac disease, SIBO, colorectal cancer.
Autoimmune & inflammatory: rheumatoid arthritis, Hashimoto’s, multiple sclerosis, psoriasis, type 1 diabetes.
Metabolic disorders: obesity, type 2 diabetes, NAFLD (Non-alcoholic fatty liver disease)
Neurological & mental health: depression, anxiety, Parkinson’s, Alzheimer’s, Autism spectrum disorders (gut dysbiosis associations reported)
Cardiovascular: atherosclerosis, hypertension.

Some researchers suggest that as many as nine out of ten chronic diseases may have links to gut dysfunction. While the exact figure may not be precise, what is clear is that the gut plays a central role in immune balance, inflammation, and metabolic health - meaning most chronic conditions are influenced by its state

Pharmaceuticals and the Gut

Pharmaceuticals are there for emergencies or when symptoms are severe and diet/lifestyle adjustments are not possible (for example, when travelling abroad or eating out frequently). They can be lifesaving and essential in the right context.

But long-term reliance is not always the answer:

Some drugs can worsen gut problems. For example, PPIs and H2 blockers, while helpful short-term, can cause gut dysbiosis if used long-term, leaving you with an even greater problem.
Overuse of antibiotics, NSAIDs, and other medications can also damage the gut lining or disrupt the microbiome.

Holistic First Approach

For most gut issues, the first line of treatment should be holistic:

What you eat - whole, unprocessed, fibre-rich, nutrient-dense foods.
How you eat - mindful eating, chewing well, not rushing meals.
When you eat - meal timing, fasting windows, circadian rhythm support.
Stress levels - stress directly affects gut motility, permeability, and microbiome balance.
Movement - regular exercise improves gut transit time and microbiome diversity.
Sleep hygiene - 7-9 hours of restorative sleep helps gut healing (8-9 for women in their 40's, 50's & 60's)
Hydration - adequate water intake supports digestion and motility.
Toxin exposure - limiting alcohol, smoking, and ultra-processed foods reduces gut stress.
Connection & relaxation - laughter, social bonds, and breathwork all support the gut-brain axis.

Addressing these areas consistently can reduce or even prevent the need for pharmaceuticals, keeping them as a tool for emergencies rather than daily crutches.